Articles | Volume 4, issue 2
https://doi.org/10.5194/pb-4-229-2017
© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
Special issue:
https://doi.org/10.5194/pb-4-229-2017
© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 4.0 License.
the Creative Commons Attribution 4.0 License.
Preface: Franz-Josef Kaup and the development of the Pathology Unit at the German Primate Center
Kerstin Mätz-Rensing
CORRESPONDING AUTHOR
German Primate Center, 37077 Göttingen, Germany
Martina Bleyer
German Primate Center, 37077 Göttingen, Germany
Related authors
Roland Plesker, Martina Bleyer, and Kerstin Mätz-Rensing
Primate Biol., 5, 7–13, https://doi.org/10.5194/pb-5-7-2018, https://doi.org/10.5194/pb-5-7-2018, 2018
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We present a spontaneous tumor of the meninges (meningioma) in a female pig-tailed macaque (Macaca nemestrina) more than 24 years old. Clinically, the monkey displayed slow, weak, and insecure movements and poor vision. A tumorous mass was present at the floor of the cranial cavity. It compressed adjacent parts of the brain, infiltrated surrounding bones, and expanded into the throat. Microscopically, the tumor showed both meningothelial and microcystic parts.
Kerstin Mätz-Rensing, Constanze Yue, Jeanette Klenner, Heinz Ellerbrok, and Christiane Stahl-Hennig
Primate Biol., 4, 163–171, https://doi.org/10.5194/pb-4-163-2017, https://doi.org/10.5194/pb-4-163-2017, 2017
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The research into therapeutic agents for prevention and treatment of orthopoxvirus (OPXV) infections requires adequate animal models to investigate the efficacy and safety of new vaccines and antiviral compounds against smallpox and other highly pathogenic OPXVs. This study was undertaken to investigate the susceptibility of rhesus monkeys towards the calpox virus, an orthopoxvirus of the species Cowpox virus, which is uniformly lethal in common marmosets, in order to define a new animal model.
Matthias Mietsch, Ulrike Sauermann, Kerstin Mätz-Rensing, Antonina Klippert, Maria Daskalaki, Nicole Stolte-Leeb, and Christiane Stahl-Hennig
Primate Biol., 4, 107–115, https://doi.org/10.5194/pb-4-107-2017, https://doi.org/10.5194/pb-4-107-2017, 2017
Eva Gruber-Dujardin, Martina Bleyer, and Kerstin Mätz-Rensing
Primate Biol., 4, 77–91, https://doi.org/10.5194/pb-4-77-2017, https://doi.org/10.5194/pb-4-77-2017, 2017
Nicole Cichon, Karen Lampe, Felix Bremmer, Tamara Becker, and Kerstin Mätz-Rensing
Primate Biol., 4, 71–75, https://doi.org/10.5194/pb-4-71-2017, https://doi.org/10.5194/pb-4-71-2017, 2017
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We herein report a unique case of granulomatous arteritis in a grey mouse lemur affecting multiple organs, which is not comparable to other disease entities formerly described in nonhuman primates. The features of the entity most closely resemble disseminated visceral giant cell arteritis in humans. A concise description of the disease is given, and the differential diagnoses are discussed. An idiopathic pathogenesis is suspected.
Karen Lampe, Jens-Christian Rudnick, Fabian Leendertz, Martina Bleyer, and Kerstin Mätz-Rensing
Primate Biol., 4, 39–46, https://doi.org/10.5194/pb-4-39-2017, https://doi.org/10.5194/pb-4-39-2017, 2017
Tamara Becker, Florian Pieper, David Liebetanz, Martina Bleyer, Annette Schrod, Kerstin Maetz-Rensing, and Stefan Treue
Primate Biol., 4, 27–32, https://doi.org/10.5194/pb-4-27-2017, https://doi.org/10.5194/pb-4-27-2017, 2017
Martina Bleyer, Marius Kunze, Eva Gruber-Dujardin, and Kerstin Mätz-Rensing
Primate Biol., 4, 17–25, https://doi.org/10.5194/pb-4-17-2017, https://doi.org/10.5194/pb-4-17-2017, 2017
N. Siskos, K. Lampe, F.-J. Kaup, and K. Mätz-Rensing
Primate Biol., 2, 9–12, https://doi.org/10.5194/pb-2-9-2015, https://doi.org/10.5194/pb-2-9-2015, 2015
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In this paper, a co-infection with Toxoplasma gondii and Capillaria hepatica in a ring-tailed lemur is described. As a protozoan parasite, T. gondii can affect nearly all warm-blooded species, causing toxoplasmosis. In lemurs, toxoplasmosis has severe clinical manifestations leading to death. C. hepatica also affects a broad range of mammals, causing hepatic capillariasis. Although it is not known to be lethal, its potential predisposition to toxoplasmosis in our case is of great interest.
Roland Plesker, Martina Bleyer, and Kerstin Mätz-Rensing
Primate Biol., 5, 7–13, https://doi.org/10.5194/pb-5-7-2018, https://doi.org/10.5194/pb-5-7-2018, 2018
Short summary
Short summary
We present a spontaneous tumor of the meninges (meningioma) in a female pig-tailed macaque (Macaca nemestrina) more than 24 years old. Clinically, the monkey displayed slow, weak, and insecure movements and poor vision. A tumorous mass was present at the floor of the cranial cavity. It compressed adjacent parts of the brain, infiltrated surrounding bones, and expanded into the throat. Microscopically, the tumor showed both meningothelial and microcystic parts.
Kerstin Mätz-Rensing, Constanze Yue, Jeanette Klenner, Heinz Ellerbrok, and Christiane Stahl-Hennig
Primate Biol., 4, 163–171, https://doi.org/10.5194/pb-4-163-2017, https://doi.org/10.5194/pb-4-163-2017, 2017
Short summary
Short summary
The research into therapeutic agents for prevention and treatment of orthopoxvirus (OPXV) infections requires adequate animal models to investigate the efficacy and safety of new vaccines and antiviral compounds against smallpox and other highly pathogenic OPXVs. This study was undertaken to investigate the susceptibility of rhesus monkeys towards the calpox virus, an orthopoxvirus of the species Cowpox virus, which is uniformly lethal in common marmosets, in order to define a new animal model.
Matthias Mietsch, Ulrike Sauermann, Kerstin Mätz-Rensing, Antonina Klippert, Maria Daskalaki, Nicole Stolte-Leeb, and Christiane Stahl-Hennig
Primate Biol., 4, 107–115, https://doi.org/10.5194/pb-4-107-2017, https://doi.org/10.5194/pb-4-107-2017, 2017
Eva Gruber-Dujardin, Martina Bleyer, and Kerstin Mätz-Rensing
Primate Biol., 4, 77–91, https://doi.org/10.5194/pb-4-77-2017, https://doi.org/10.5194/pb-4-77-2017, 2017
Nicole Cichon, Karen Lampe, Felix Bremmer, Tamara Becker, and Kerstin Mätz-Rensing
Primate Biol., 4, 71–75, https://doi.org/10.5194/pb-4-71-2017, https://doi.org/10.5194/pb-4-71-2017, 2017
Short summary
Short summary
We herein report a unique case of granulomatous arteritis in a grey mouse lemur affecting multiple organs, which is not comparable to other disease entities formerly described in nonhuman primates. The features of the entity most closely resemble disseminated visceral giant cell arteritis in humans. A concise description of the disease is given, and the differential diagnoses are discussed. An idiopathic pathogenesis is suspected.
Karen Lampe, Jens-Christian Rudnick, Fabian Leendertz, Martina Bleyer, and Kerstin Mätz-Rensing
Primate Biol., 4, 39–46, https://doi.org/10.5194/pb-4-39-2017, https://doi.org/10.5194/pb-4-39-2017, 2017
Tamara Becker, Florian Pieper, David Liebetanz, Martina Bleyer, Annette Schrod, Kerstin Maetz-Rensing, and Stefan Treue
Primate Biol., 4, 27–32, https://doi.org/10.5194/pb-4-27-2017, https://doi.org/10.5194/pb-4-27-2017, 2017
Martina Bleyer, Marius Kunze, Eva Gruber-Dujardin, and Kerstin Mätz-Rensing
Primate Biol., 4, 17–25, https://doi.org/10.5194/pb-4-17-2017, https://doi.org/10.5194/pb-4-17-2017, 2017
Antonina Klippert, Martina Bleyer, Ulrike Sauermann, Berit Neumann, Artur Kaul, Maria Daskalaki, Nicole Stolte-Leeb, Frank Kirchhoff, and Christiane Stahl-Hennig
Primate Biol., 3, 65–75, https://doi.org/10.5194/pb-3-65-2016, https://doi.org/10.5194/pb-3-65-2016, 2016
Short summary
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Despite effective antiviral therapy, HIV infection frequently leads to blood cell tumors known as lymphoma in the final disease stage. We have observed the same tumors in monkeys infected with simian immunodeficiency virus. Tumor development coincided with and was fostered by co-infection with the tumorigenic simian homolog to human Epstein–Barr virus. Two cases of lymphoma are presented, one exhibiting an unusual cell surface marker composition and the other obstructing the urogenital tract.
N. Siskos, K. Lampe, F.-J. Kaup, and K. Mätz-Rensing
Primate Biol., 2, 9–12, https://doi.org/10.5194/pb-2-9-2015, https://doi.org/10.5194/pb-2-9-2015, 2015
Short summary
Short summary
In this paper, a co-infection with Toxoplasma gondii and Capillaria hepatica in a ring-tailed lemur is described. As a protozoan parasite, T. gondii can affect nearly all warm-blooded species, causing toxoplasmosis. In lemurs, toxoplasmosis has severe clinical manifestations leading to death. C. hepatica also affects a broad range of mammals, causing hepatic capillariasis. Although it is not known to be lethal, its potential predisposition to toxoplasmosis in our case is of great interest.
Special issue