Articles | Volume 4, issue 1
Primate Biol., 4, 27–32, 2017

Special issue: Special diseases of nonhuman primates

Primate Biol., 4, 27–32, 2017

Research article 07 Mar 2017

Research article | 07 Mar 2017

Suspect Guillain-Barré syndrome in a male rhesus macaque (Macaca mulatta)

Tamara Becker1, Florian Pieper1, David Liebetanz2, Martina Bleyer1, Annette Schrod1, Kerstin Maetz-Rensing1, and Stefan Treue1 Tamara Becker et al.
  • 1German Primate Center, 37077 Göttingen, Germany
  • 2Georg August University, University Hospital, 37075 Göttingen, Germany

Abstract. Guillain-Barré syndrome (GBS) is a rare, mainly acute inflammatory polyneuropathy in humans. It is frequently post-infectious with auto antibodies being formed against myelin sheaths, resulting in a progressive and more-or-less severe paralysis of the motor neuron and cranial nerves. Mortality is low and 60 % of the patients recover completely from the disease after intensive treatment.

In animals, there are a few diseases that closely resemble GBS, but cases of GBS in monkeys seem to be scarce. In this case report, the clinical course of a progressive tetraplegia in a male rhesus macaque is described. Clinical, cerebrospinal fluid (CSF), electroneurography (ENG) and electromyography (EMG), and pathological findings revealed symptoms very similar to human GBS.