Articles | Volume 4, issue 1
Primate Biol., 4, 71–75, 2017
https://doi.org/10.5194/pb-4-71-2017

Special issue: Special diseases of nonhuman primates

Primate Biol., 4, 71–75, 2017
https://doi.org/10.5194/pb-4-71-2017

Short communication 03 Apr 2017

Short communication | 03 Apr 2017

Unique case of granulomatous arteritis in a grey mouse lemur (Microcebus murinus) – first case description

Nicole Cichon1, Karen Lampe1, Felix Bremmer2, Tamara Becker1, and Kerstin Mätz-Rensing1 Nicole Cichon et al.
  • 1German Primate Center, Kellnerweg 4, 37077 Göttingen, Germany
  • 2Georg-August-Universität, Universitätsmedizin Göttingen, Robert Kochstr. 40, 37075 Göttingen, Germany

Abstract. Overall, diseases of the vascular system are rarely observed entities among nonhuman primates that are commonly associated with systemic infections, septicemia or bacteremia. Rhesus monkeys infected with simian immunodeficiency virus (SIV) may develop a chronic occlusive arteriopathy of unknown etiology in late stages of the disease. This SIV associated arteriopathy is the only well-known specific vascular entity described in nonhuman primates. We herein report a unique case of granulomatous arteritis in a grey mouse lemur affecting multiple organs, which is not comparable to other disease entities formerly described in nonhuman primates. The features of the entity most closely resemble disseminated visceral giant cell arteritis in humans. A concise description of the disease is given, and the differential diagnoses are discussed. An idiopathic pathogenesis is suspected.

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Short summary
We herein report a unique case of granulomatous arteritis in a grey mouse lemur affecting multiple organs, which is not comparable to other disease entities formerly described in nonhuman primates. The features of the entity most closely resemble disseminated visceral giant cell arteritis in humans. A concise description of the disease is given, and the differential diagnoses are discussed. An idiopathic pathogenesis is suspected.