Articles | Volume 4, issue 2
https://doi.org/10.5194/pb-4-215-2017
© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
https://doi.org/10.5194/pb-4-215-2017
© Author(s) 2017. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
Review article
| 
27 Oct 2017
Review article |
| 27 Oct 2017
A review on ocular findings in mouse lemurs: potential links to age and genetic background
Marko Dubicanac
Institute of Zoology, University of Veterinary Medicine Hannover,
Buenteweg 17, 30559 Hannover, Germany
Ute Radespiel
Institute of Zoology, University of Veterinary Medicine Hannover,
Buenteweg 17, 30559 Hannover, Germany
Elke Zimmermann
CORRESPONDING AUTHOR
Institute of Zoology, University of Veterinary Medicine Hannover,
Buenteweg 17, 30559 Hannover, Germany
Related subject area
Pathology
Multiple adenomas of the thyroid gland in an African green monkey (Chlorocebus aethiops)
Spontaneous (Hashimoto-like) chronic lymphocytic thyroiditis in a rhesus macaque (Macaca mulatta)
Reactive mesothelial hyperplasia mimicking mesothelioma in an African green monkey (Chlorocebus aethiops)
Spontaneous meningioma in a pig-tailed macaque (Macaca nemestrina)
Spontaneous endometriosis in rhesus macaques: evidence for a genetic association with specific Mamu-A1 alleles
Morphological and immunohistochemical characterization of spontaneous endometriosis in rhesus macaques (Macaca mulatta)
Unique case of granulomatous arteritis in a grey mouse lemur (Microcebus murinus) – first case description
A case of gallstones in an African green monkey (Chlorocebus aethiops)
Intravascular T-cell lymphoma in a patas monkey (Erythrocebus patas)
Spontaneous lung pathology in a captive common marmoset colony (Callithrix jacchus)
The Department of Pathology at the German Primate Center from 1973 to 1999
From the working group "Experimental Pathology" to the department "Pathology Unit" – historical development in retrospect
Unique case of disseminated toxoplasmosis and concurrent hepatic capillariasis in a ring-tailed lemur: first case description
Roland Plesker and Kernt Köhler
Primate Biol., 10, 1–6, https://doi.org/10.5194/pb-10-1-2023, https://doi.org/10.5194/pb-10-1-2023, 2023
Short summary
Short summary
To our knowledge, this report represents the first description of thyroid gland tumors in an African Green Monkey (Chlorocebus aethiops). Two cystadenomas as well as a solid follicular adenoma are described in a 27-year-old female. No indications of excessive hormone production due to the tumors were detected.
Roland Plesker and Gudrun Hintereder
Primate Biol., 8, 37–42, https://doi.org/10.5194/pb-8-37-2021, https://doi.org/10.5194/pb-8-37-2021, 2021
Short summary
Short summary
To our knowledge, this study is the first report of spontaneous Hashimoto-like chronic lymphocytic thyroiditis in a rhesus macaque (Macaca mulatta). Despite the microscopic similarities to human cases, autoantibodies (thyroglobulin antibodies, thyriod peroxidase antibodies, and thyroid-stimulating hormone receptor antibodies) were not identified in this rhesus macaque using a human electrochemiluminescence immunoassay system.
Roland Plesker, Kernt Köhler, Susanne von Gerlach, Klaus Boller, Markus Vogt, and Inke S. Feder
Primate Biol., 7, 5–12, https://doi.org/10.5194/pb-7-5-2020, https://doi.org/10.5194/pb-7-5-2020, 2020
Short summary
Short summary
This report describes a reactive mesothelial hyperplasia as a reaction to a polyserositis in an African green monkey (Chlorocebus aethiops) mimicking an epitheloid mesothelioma. Histopathology, immunohistochemistry, fluorescence in situ hybridization, and electron microscopy were used to determine the benign nature of the mesothelial proliferation. For the first time, human genetic probes had been successfully applied to an African green monkey.
Roland Plesker, Martina Bleyer, and Kerstin Mätz-Rensing
Primate Biol., 5, 7–13, https://doi.org/10.5194/pb-5-7-2018, https://doi.org/10.5194/pb-5-7-2018, 2018
Short summary
Short summary
We present a spontaneous tumor of the meninges (meningioma) in a female pig-tailed macaque (Macaca nemestrina) more than 24 years old. Clinically, the monkey displayed slow, weak, and insecure movements and poor vision. A tumorous mass was present at the floor of the cranial cavity. It compressed adjacent parts of the brain, infiltrated surrounding bones, and expanded into the throat. Microscopically, the tumor showed both meningothelial and microcystic parts.
Ivanela Kondova, Gerco Braskamp, Peter J. Heidt, Wim Collignon, Tom Haaksma, Nanine de Groot, Nel Otting, Gaby Doxiadis, Susan V. Westmoreland, Eric J. Vallender, and Ronald E. Bontrop
Primate Biol., 4, 117–125, https://doi.org/10.5194/pb-4-117-2017, https://doi.org/10.5194/pb-4-117-2017, 2017
Eva Gruber-Dujardin, Martina Bleyer, and Kerstin Mätz-Rensing
Primate Biol., 4, 77–91, https://doi.org/10.5194/pb-4-77-2017, https://doi.org/10.5194/pb-4-77-2017, 2017
Nicole Cichon, Karen Lampe, Felix Bremmer, Tamara Becker, and Kerstin Mätz-Rensing
Primate Biol., 4, 71–75, https://doi.org/10.5194/pb-4-71-2017, https://doi.org/10.5194/pb-4-71-2017, 2017
Short summary
Short summary
We herein report a unique case of granulomatous arteritis in a grey mouse lemur affecting multiple organs, which is not comparable to other disease entities formerly described in nonhuman primates. The features of the entity most closely resemble disseminated visceral giant cell arteritis in humans. A concise description of the disease is given, and the differential diagnoses are discussed. An idiopathic pathogenesis is suspected.
Dina Kleinlützum and Roland Plesker
Primate Biol., 4, 33–37, https://doi.org/10.5194/pb-4-33-2017, https://doi.org/10.5194/pb-4-33-2017, 2017
Karen Lampe, Jens-Christian Rudnick, Fabian Leendertz, Martina Bleyer, and Kerstin Mätz-Rensing
Primate Biol., 4, 39–46, https://doi.org/10.5194/pb-4-39-2017, https://doi.org/10.5194/pb-4-39-2017, 2017
Martina Bleyer, Marius Kunze, Eva Gruber-Dujardin, and Kerstin Mätz-Rensing
Primate Biol., 4, 17–25, https://doi.org/10.5194/pb-4-17-2017, https://doi.org/10.5194/pb-4-17-2017, 2017
M. Brack
Primate Biol., 2, 81–87, https://doi.org/10.5194/pb-2-81-2015, https://doi.org/10.5194/pb-2-81-2015, 2015
F.-J. Kaup
Primate Biol., 2, 57–63, https://doi.org/10.5194/pb-2-57-2015, https://doi.org/10.5194/pb-2-57-2015, 2015
N. Siskos, K. Lampe, F.-J. Kaup, and K. Mätz-Rensing
Primate Biol., 2, 9–12, https://doi.org/10.5194/pb-2-9-2015, https://doi.org/10.5194/pb-2-9-2015, 2015
Short summary
Short summary
In this paper, a co-infection with Toxoplasma gondii and Capillaria hepatica in a ring-tailed lemur is described. As a protozoan parasite, T. gondii can affect nearly all warm-blooded species, causing toxoplasmosis. In lemurs, toxoplasmosis has severe clinical manifestations leading to death. C. hepatica also affects a broad range of mammals, causing hepatic capillariasis. Although it is not known to be lethal, its potential predisposition to toxoplasmosis in our case is of great interest.
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Short summary
This review shows that mouse lemurs show various ocular impairments which may distort vision. The most widespread and obvious ocular finding were nuclear sclerosis and cataracts. Both highly increase with increasing age. Iris posterior synechia has been described in different colonies and seems highly age dependent and cataract associated. Combined with the variety of many other eye diseases, special ophthalmological treatments and examinations are required to ensure animal well-being.
This review shows that mouse lemurs show various ocular impairments which may distort vision....
