Articles | Volume 4, issue 2
Primate Biol., 4, 185–213, 2017
https://doi.org/10.5194/pb-4-185-2017

Special issue: Stem cells in non-human primates

Primate Biol., 4, 185–213, 2017
https://doi.org/10.5194/pb-4-185-2017

Review article 11 Oct 2017

Review article | 11 Oct 2017

Transplantation in the nonhuman primate MPTP model of Parkinson's disease: update and perspectives

Florence Wianny and Julien Vezoli

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Cited articles

Adler, C. H. and Thorpy, M. J.: Sleep issues in Parkinson's disease, Neurology, 64, 12 Suppl. 3, S12–20, 2015.
Agid, Y.: Parkinson's disease: pathophysiology, Lancet, 337, 1321–1324, 1991.
Almirall, H., Pigarev, I., de la Calzada, M. D., Pigareva, M., Herrero, M. T., and Sagales, T.: Nocturnal sleep structure and temperature slope in MPTP treated monkeys, J. Neural Transm., 106, 1125–1134, 1999.
Almirall, H., Bautista, V., Sanchez-Bahillo, A., and Trinidad-Herrero, M.: Ultradian and circadian body temperature and activity rhythms in chronic MPTP treated monkeys, Neurophysiol. Clin., 31, 161–170, 2001.
Annett, L. E., Dunnett, S. B., Martel, F. L., Rogers, D. C., Ridley, R. M., Baker, H. F., and Marsden, C. D.: A functional assessment of embryonic dopaminergic grafts in the marmoset, Prog. Brain Res., 82, 535–542, 1990.
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Short summary
We propose for this special issue an exhaustive review of past and most recent advances on the topic of cell replacement in Parkinson’s disease, describing the different procedures using transplantation of various cell sources as a therapeutic approach and linked therapeutic behavioral and/or functional outcomes. We conclude by opening perspectives on future promising developments for the use of cell-replacement therapy in research and its translation to the clinic.