Articles | Volume 3, issue 1
https://doi.org/10.5194/pb-3-9-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
https://doi.org/10.5194/pb-3-9-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
the Creative Commons Attribution 3.0 License.
Review article
| 
12 Feb 2016
Review article |
| 12 Feb 2016
The common marmoset (Callithrix jacchus): a relevant preclinical model of human (auto)immune-mediated inflammatory disease of the brain
Bert A. 't Hart
CORRESPONDING AUTHOR
Department Immunobiology, Biomedical Primate Research Centre, Rijswijk, the Netherlands
Jordon Dunham
Department Immunobiology, Biomedical Primate Research Centre, Rijswijk, the Netherlands
S. Anwar Jagessar
Department Immunobiology, Biomedical Primate Research Centre, Rijswijk, the Netherlands
Yolanda S. Kap
Department Immunobiology, Biomedical Primate Research Centre, Rijswijk, the Netherlands
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Short summary
The increasing prevalence of chronic autoimmune inflammatory disorders (AIMIDs) in aging human populations creates a high unmet need for safe and effective medications. However, thus far the translation of pathogenic concepts developed in animal models into effective treatments for the patient has been notoriously difficult. The main reason is that currently used mouse-based animal models for the pipeline selection of promising new treatments were insufficiently predictive for clinical success.
The increasing prevalence of chronic autoimmune inflammatory disorders (AIMIDs) in aging human...
