Primate Biology
Primate Biology
Primate Biology
Articles | Volume 3, issue 1
Articles | Volume 3, issue 1
https://doi.org/10.5194/pb-3-9-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
https://doi.org/10.5194/pb-3-9-2016
© Author(s) 2016. This work is distributed under
the Creative Commons Attribution 3.0 License.
Articles | Volume 3, issue 1
Review article
 | 
12 Feb 2016
Review article |  | 12 Feb 2016

The common marmoset (Callithrix jacchus): a relevant preclinical model of human (auto)immune-mediated inflammatory disease of the brain

Bert A. 't Hart, Jordon Dunham, S. Anwar Jagessar, and Yolanda S. Kap

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Latest update: 23 Nov 2024
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Short summary
The increasing prevalence of chronic autoimmune inflammatory disorders (AIMIDs) in aging human populations creates a high unmet need for safe and effective medications. However, thus far the translation of pathogenic concepts developed in animal models into effective treatments for the patient has been notoriously difficult. The main reason is that currently used mouse-based animal models for the pipeline selection of promising new treatments were insufficiently predictive for clinical success.
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