Articles | Volume 2, issue 1
Primate Biol., 2, 65–69, 2015
https://doi.org/10.5194/pb-2-65-2015

Special issue: Hans-Jürg Kuhn and the German Primate Center

Primate Biol., 2, 65–69, 2015
https://doi.org/10.5194/pb-2-65-2015
Review article
24 Aug 2015
Review article | 24 Aug 2015

Immunodeficiency viruses and prion disease

W. Bodemer

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Short summary
Lentiviral immunodeficiency viruses cause AIDS in humans and in non-human primates. Macaques are a suitable animal model to study infection, disease and the immune response against the retrovirus. As to prion disease, we established a rhesus monkey infection model for this unique infectious pathogen. Animals were experimentally infected with human and bovine prions. Unlike in human prion disease (Creutzfeldt-Jakob disease), we observed early and late stages of disease.