Articles | Volume 6, issue 2
Primate Biol., 6, 75–86, 2019
https://doi.org/10.5194/pb-6-75-2019
Primate Biol., 6, 75–86, 2019
https://doi.org/10.5194/pb-6-75-2019
Research article
29 Jul 2019
Research article | 29 Jul 2019

Baboon induced pluripotent stem cell generation by piggyBac transposition of reprogramming factors

Ignacio Rodriguez-Polo et al.

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Latest update: 30 Jun 2022
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Short summary
Stem-cell-based regenerative therapies in patients, e.g., for a failing heart or Parkinson's disease, are within reach. However, studies in appropriate animal models are required to make the final step to the clinic. In this context, the baboon may represent a valuable animal model for specific purposes. Here, we generated five so-called induced pluripotent stem cell lines from the baboon, which may be useful for preclinical testing of the respective therapeutic approaches.