Primate Biology
Primate Biology
Primate Biology
Articles | Volume 6, issue 2
Articles | Volume 6, issue 2
https://doi.org/10.5194/pb-6-75-2019
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/pb-6-75-2019
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 6, issue 2
Research article
 | 
29 Jul 2019
Research article |  | 29 Jul 2019

Baboon induced pluripotent stem cell generation by piggyBac transposition of reprogramming factors

Ignacio Rodriguez-Polo, Michael Stauske, Alexander Becker, Iris Bartels, Ralf Dressel, and Rüdiger Behr

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Latest update: 11 Jul 2025
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Short summary
Stem-cell-based regenerative therapies in patients, e.g., for a failing heart or Parkinson's disease, are within reach. However, studies in appropriate animal models are required to make the final step to the clinic. In this context, the baboon may represent a valuable animal model for specific purposes. Here, we generated five so-called induced pluripotent stem cell lines from the baboon, which may be useful for preclinical testing of the respective therapeutic approaches.
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