Primate Biology
Primate Biology
Primate Biology
Articles | Volume 6, issue 2
Articles | Volume 6, issue 2
https://doi.org/10.5194/pb-6-65-2019
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.
https://doi.org/10.5194/pb-6-65-2019
© Author(s) 2019. This work is distributed under
the Creative Commons Attribution 4.0 License.
Articles | Volume 6, issue 2
Research article
 | 
12 Jul 2019
Research article |  | 12 Jul 2019

Effect of ovariectomy on proximal tibia metaphysis and lumbar vertebral body in common marmoset monkeys

Christina Schlumbohm, Dana Seidlová-Wuttke, and Eberhard Fuchs

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Short summary
We investigated the effect of estrogen withdrawal on bone tissue in adult female marmoset monkeys. Bone mineral density (BMD) of the proximal tibia and the second-last lumbar vertebral body was monitored before and up to 12 months after ovariectomy. All animals lost BMD in proximal tibia, but not in the vertebra. This supports the idea that ovariectomized marmoset monkeys may serve as a model for anti-osteoporosis drug testing.
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