Articles | Volume 4, issue 2
Primate Biol., 4, 163–171, 2017
https://doi.org/10.5194/pb-4-163-2017

Special issue: Special diseases of nonhuman primates

Primate Biol., 4, 163–171, 2017
https://doi.org/10.5194/pb-4-163-2017
Research article
11 Sep 2017
Research article | 11 Sep 2017

Limited susceptibility of rhesus macaques to a cowpox virus isolated from a lethal outbreak among New World monkeys

Kerstin Mätz-Rensing et al.

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Short summary
The research into therapeutic agents for prevention and treatment of orthopoxvirus (OPXV) infections requires adequate animal models to investigate the efficacy and safety of new vaccines and antiviral compounds against smallpox and other highly pathogenic OPXVs. This study was undertaken to investigate the susceptibility of rhesus monkeys towards the calpox virus, an orthopoxvirus of the species Cowpox virus, which is uniformly lethal in common marmosets, in order to define a new animal model.